Lazio vs Pisa Prediction: Key Stats, Tips and Lineups

Lazio bring the curtain down on their Serie A campaign at the Stadio Olimpico in Rome on 23 May 2026, hosting already-doomed Pisa in the final round of the regular season. With the home side sitting in mid-table and the visitors rooted to the bottom, this clash pitches a solid but inconsistent Lazio outfit against a Pisa team that has struggled badly at this level.

The standings underline the contrasting trajectories. Lazio are 9th with 51 points from 37 matches, having scored and conceded 39 goals, while Pisa are 20th on just 18 points, with a damaging goal difference of -44 after conceding 69 times. For Lazio, this is a chance to lock in a top-half finish and give their supporters a positive send-off. For Pisa, it is about salvaging some pride after a torrid season that has already consigned them to relegation.

From a betting perspective, Lazio vs Pisa in Serie A offers a classic end-of-season dynamic: a strong favourite at home, a vulnerable defence in the away ranks, and clear statistical indicators pointing towards a home win. With bookmakers heavily siding with Lazio and predictive metrics also favouring the hosts, this fixture stands out for those looking at match winner markets and cautious goal-based angles.

Lazio vs Pisa Key Stats

• Lazio sit 9th in Serie A with 51 points from 37 games, scoring 39 and conceding 39.
• The only recent meeting in this campaign ended Pisa 0-0 Lazio in Serie A on 30 October 2025 at Arena Garibaldi - Stadio Romeo Anconetani.
• Lazio have kept 15 clean sheets in the league, compared to just 5 for Pisa.

Lazio vs Pisa — Tale of the Tape

• Position: 9 vs 20
• Points: 51 vs 18
• Goals For: 39 vs 25
• Goals Against: 39 vs 69
• Clean Sheets: Lazio 15, Pisa 5

The season record shows a clear gulf between the sides. Lazio’s balanced tally of 39 goals scored and 39 conceded from 37 matches reflects a team that has been competitive in most games, with 13 wins and 12 draws keeping them firmly in the top half. Their home return of 7 wins, 6 draws and 5 defeats, with 25 goals scored at the Stadio Olimpico, underpins their status as strong favourites here.

Pisa, by contrast, have endured a brutal campaign. Bottom of the table with only 2 wins from 37 fixtures, they have shipped 69 goals – almost 1.9 per game – while averaging just 0.7 goals scored. Away from home they are still without a victory, with 0 wins, 8 draws and 10 defeats, conceding 43 goals in 18 away matches. The combination of a fragile defence and blunt attack makes survival in Rome a daunting task.

Lazio vs Pisa Key Matchups

Alessio Romagnoli vs A. Caracciolo

With no leading scorers data available, the defensive battle becomes central. For Lazio, Alessio Romagnoli has been a mainstay at the back, making 31 league appearances and starting 30 of them. He has contributed 1 red card but also strong defensive numbers, including 23 tackles, 19 blocks and 31 interceptions, supported by 1,942 passes at an impressive 93% accuracy. His ability to build from the back and dominate duels (101 won from 168) will be key against a Pisa side that struggles to create clear chances.

On the Pisa side, Antonio Aldo Caracciolo has been one of the busiest defenders in Serie A this term, with 35 appearances and 3,074 minutes. He has chipped in with 2 goals and 20 shots, but his main workload has been defensive: 71 tackles, 24 blocks and 51 interceptions, plus 261 duels with 139 won. However, his 10 yellow cards underline how often he has been under pressure. Against Lazio’s more technically secure attack, his disciplinary record and heavy minutes could again be tested.

M. Zaccagni vs M. Aebischer

Mattia Zaccagni has provided important attacking thrust for Lazio, making 26 appearances and scoring 3 goals. He has attempted 60 dribbles with 23 successful, and drawn 82 fouls – a sign of how often he forces defenders into mistakes. His 35 key passes and 773 completed passes at 82% accuracy make him a creative outlet who can unpick Pisa’s defensive block. Even though he has 6 yellow cards and 1 red, his forward impact is significant when on the pitch.

For Pisa, Michel Aebischer has been a central figure in midfield, appearing 34 times and starting 32. He has 1 goal and 1 assist, but his influence comes through 1,490 passes at 85% accuracy and 33 key passes, indicating he is the main conduit in possession. Defensively, 64 tackles and 35 interceptions show his work rate, though 8 yellow cards highlight disciplinary risk. His battle to control midfield against Lazio’s press and disruptors like Zaccagni will be crucial if Pisa are to escape sustained pressure.

Head-to-Head: Last Meetings

Recent head-to-head history between these sides in the top flight is limited, with just one clash in the current campaign. That meeting was tight and low-scoring, reflecting Pisa’s defensive approach and Lazio’s difficulty in breaking them down away from home.

• 30 October 2025: Pisa 0-0 Lazio (Serie A)

Lazio vs Pisa Prediction

Analysis points to a match where Lazio dominate territory and possession against a Pisa side that has lost all of its last five league games and carries the worst defensive record in the division. Lazio’s league form string of LLWDW suggests inconsistency, but they come into the finale with momentum and a strong underlying profile: 15 clean sheets and only 39 goals conceded in 37 matches.

Pisa’s league form of LLLLL underlines a collapse in the run-in, with their last five outings yielding just 2 goals scored and 11 conceded. With the prediction metrics giving Lazio a 45% win probability and Pisa only 10%, and home advantage at the Stadio Olimpico, everything points towards a home victory, potentially with a clean sheet if Lazio maintain their defensive standards.

Predicted Score: Lazio 1-0 Pisa

Lazio League Form

LLWDW

Pisa League Form

LLLLL

Lazio Possible Starting Lineup

A. Furlanetto; S. Gigot, Mario Gila, A. Romagnoli, L. Pellegrini; T. Bašić, D. Cataldi, F. Dele-Bashiru; M. Lazzari, T. Noslin, Pedro.

Lazio have consistently favoured a back four and a three-man midfield, with data indicating 4-3-3 as their most used shape. The presence of ball-playing centre-backs like Romagnoli and Mario Gila, supported by full-backs such as L. Pellegrini and M. Lazzari, allows them to build from deep. In attack, experienced figures like Pedro and T. Noslin can stretch Pisa’s back line, while D. Cataldi and F. Dele-Bashiru provide balance in midfield. However, the absence of several key squad members reduces rotation options, so the core XI will be expected to carry the load.

Pisa Possible Starting Lineup

S. Scuffet; S. Canestrelli, A. Calabresi, R. Bozhinov; M. Aebischer, I. Touré, M. Marin, C. Stengs; R. Durosinmi, S. Iling-Junior.

Pisa have alternated between three- and five-man defensive systems, with 3-5-2 their most common setup. A back line anchored by S. Canestrelli and A. Calabresi in front of S. Scuffet is likely to sit deep, while midfielders such as M. Aebischer and I. Touré work to disrupt Lazio’s rhythm and launch transitions. Wide players like C. Stengs and forwards such as R. Durosinmi and S. Iling-Junior will be tasked with exploiting counter-attacking opportunities. Injuries and suspensions, particularly in defence, may force some reshuffling and limit their ability to press high.

Lazio Team News

Lazio face a lengthy absentee list. Goalkeeper E. Motta is out with injury, while Patric misses the match due to a muscle injury. First-choice goalkeeper I. Provedel is sidelined with a shoulder injury. In midfield, N. Rovella is suspended after a red card, and K. Taylor is unavailable due to yellow cards. At full-back, Nuno Tavares also misses out through yellow card suspension, and in attack M. Zaccagni is ruled out with a knee injury. These absences will test squad depth, especially in defence and wide areas.

Pisa Team News

Pisa are also depleted. Defender A. Caracciolo is suspended due to yellow cards, removing a key figure from their back line. F. Coppola is out with a muscle injury, while D. Denoon misses the game with an ankle injury. Midfielder Lorran is listed as inactive, and creative option M. Tramoni is sidelined by a muscle injury. Forward S. Moreo is questionable with an injury, further limiting attacking options for the already goal-shy visitors.

Injuries & Suspensions

Lazio:

• E. Motta — Reason: Injury
• Patric — Reason: Muscle Injury
• I. Provedel — Reason: Shoulder Injury
• N. Rovella — Reason: Red Card
• N. Tavares — Reason: Yellow Cards
• K. Taylor — Reason: Yellow Cards
• M. Zaccagni — Reason: Knee Injury

Pisa:

• A. Caracciolo — Reason: Yellow Cards
• F. Coppola — Reason: Muscle Injury
• D. Denoon — Reason: Ankle Injury
• Lorran — Reason: Inactive
• M. Tramoni — Reason: Muscle Injury
• S. Moreo — Reason: Injury (Questionable)

Betting Tips: Lazio vs Pisa

Exactly 3 distinct tips from different markets:

• Result Tip: Back Lazio to win. With a 45% implied win probability against Pisa’s 10%, superior form and home advantage, the hosts are rightly strong favourites. Across major bookmakers, home odds range around 1.47–1.61, with options including 1.55 at Bet365 and 1.57 at Betfair and Pinnacle, offering a solid anchor for accumulators or a single stake.
• Goals Tip: Under 3.5 goals appeals. Lazio average 1.1 goals scored and 1.1 conceded per match, while Pisa average 0.7 scored and 1.9 conceded. The previous head-to-head finished 0-0, and Lazio’s 15 clean sheets suggest they can control the game without needing a high-scoring contest. Look to combine a cautious goals line with the match result in a builder market where available, using the strong home odds (e.g. 1.55 Lazio win at Bet365) as a base.
• Value Tip: Lazio win to nil. Pisa have failed to score in 21 of 37 league matches, and Lazio’s defensive record plus 15 clean sheets indicate good potential for a shutout. While exact “win to nil” odds are not listed, you can infer a premium over the straight home price; pairing Lazio’s home odds (for example 1.57 at Betfair or Pinnacle) with Pisa’s attacking struggles offers a value angle in correct-score or clean-sheet markets.

How to Watch Lazio vs Pisa

Broadcast coverage varies by region. General guide:

• Spain: Movistar LaLiga
• UK: Premier Sports
• Australia: beIN Sports
• India: FanCode
• MENA: beIN Sports
• South America: ESPN / Disney+
• Africa: SuperSport

Odds are accurate at the time of writing and subject to change. Please gamble responsibly.